Tissue repair research peptides

Angiogenic, actin-binding and anti-inflammatory sequences — the eleven compounds Amino Club supplies for tissue remodelling, gut and inflammatory signalling research.

What this group covers

Tissue repair research peptides are studied for their role in the sequence that follows injury: vascular response, cell migration, matrix remodelling and the resolution of inflammation. This is the largest group in the Amino Club peptides catalogue, and the mechanisms inside it are genuinely distinct rather than variations on one theme.

BPC-157 is a synthetic fragment of a gastric protective protein, investigated for angiogenic signalling and for effects on the gut lining. TB-500 is the synthetic actin-binding region of thymosin beta-4 and works through cell migration and actin sequestration instead. Because the two are mechanistically independent they are often run together, which is the basis of the BPC-157 / TB-500 preparation. The difference between them is set out on the BPC-157 versus TB-500 comparison.

The inflammatory arm holds KPV, the C-terminal tripeptide of alpha-MSH, LL-37, the human cathelicidin fragment, and VIP, vasoactive intestinal peptide. ARA-290 is an eleven-residue erythropoietin derivative studied for tissue-protective signalling without the haematopoietic activity. Cartlax is directed at cartilage matrix work and Dermorphin at opioid receptor signalling.

Lyophilised vials and intranasal presentations

Most of this group is supplied lyophilised in sealed vials. Three are also offered ready to use in 15ml metered intranasal bottles, where no reconstitution step is required: BPC-157 nasal spray and the combined BPC-157 / TB-500 nasal spray. The presentation changes the handling requirements rather than the material, and the choice is usually made on the basis of the experimental design rather than convenience.

The complete group with current strengths is on the tissue and repair category page.

Purity, presentation and handling

Every compound here is specified at 99% purity or better by HPLC with identity confirmed by mass spectrometry, released against the Certificate of Analysis for its own batch, and the batch number on the certificate matches the number on the vial label. The release process is documented on the lab testing page.

Post-reconstitution stability varies widely across this group. LL-37 is a cationic antimicrobial sequence with adsorption behaviour that does not generalise from the rest of the catalogue, and the short tripeptides behave differently again from the forty-plus residue sequences. Handling notes therefore sit on each product page. Reconstitution consumables are under lab supplies.

Compound guides in this group

Individual guides to the compounds in this group.

BPC-157 — a gastric protein fragment studied for angiogenic signalling.
TB-500 — the actin-binding region of thymosin beta-4.
ARA-290 — the tissue-protective face of erythropoietin, separated from the rest.
KPV — three residues from alpha-MSH, carrying its anti-inflammatory activity.
LL-37 — the only human cathelicidin, antimicrobial and immunomodulatory by turns.
VIP — studied for immune regulation and for circadian timing.
Dermorphin — an amphibian opioid heptapeptide and reference mu agonist.

Research use only

All tissue repair research peptides listed here are laboratory reference materials. They are not medicines, not supplements, and not for human or veterinary use, and no dosing guidance or administration protocol is provided for any of them. The full terms are in the research use policy.