Melanotan II supplied in solution in a metered intranasal bottle — the same cyclic heptapeptide, no reconstitution step.
- Contains
- Melanotan II (sequence, formula and CAS number are on the vial product page)
- Content
- 15mg in a metered 15ml bottle
- Presentation
- ready-to-use metered intranasal solution; no reconstitution step
- Purity
- ≥99% by HPLC, identity confirmed by mass spectrometry
- Released against
- the Certificate of Analysis for its own batch
About Melanotan II Nasal Spray
This is Melanotan II, the cyclic non-selective melanocortin agonist, supplied in a metered 15ml intranasal bottle rather than as a lyophilised cake. The compound is the same; what differs is that the concentration is fixed and verified before it reaches the bench.
Removing the reconstitution step removes a source of between-run variability, which matters for protocols that need consistency across sessions more than they need control over concentration.
What the research covers
The research context is unchanged from the vial: MC1R-mediated pigmentation, and central MC3R and MC4R signalling in appetite and arousal. Because the compound is non-selective, attribution still requires the MC1R-selective Melanotan I as a comparator.
Where the intranasal route is part of the experimental question rather than incidental, this presentation is the relevant one. The Melanotan II page covers the pharmacology. The skin and cosmetic research peptides hub covers the three mechanisms in this group.
Handling Melanotan II Nasal Spray
Supplied as a metered preparation, so there is no reconstitution step and no reconstitution error, but equally no opportunity to set the concentration.
Store cold and upright, protect from light. A cyclic peptide already in aqueous solution has a shorter usable life than a sealed lyophilised vial, so this format trades shelf life for immediate usability.
Other formats
The same compound is supplied as a lyophilised Melanotan II vial, which gives control over concentration that a fixed solution cannot.
Common questions about Melanotan II Nasal Spray
Is this the same compound as the Melanotan II vial?
Yes. The compound is identical; it is supplied already in solution in a metered intranasal bottle instead of as a lyophilised powder.
When is the nasal spray the better choice?
When the intranasal route is itself part of the study design, or when consistency between sessions matters more than control over concentration.
When is the vial the better choice?
When the protocol needs to set its own concentration or run dose-ranging. A fixed-concentration solution cannot be varied.
How long does the spray remain usable?
A peptide in solution has a shorter usable life than a sealed lyophilised vial. Keep the bottle cold, upright and protected from light, and treat its life as limited.

